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Radiation causes tissue damage by dysregulating inflammasome–gasdermin D signaling in both host and transplanted cells
Radiotherapy is a commonly used conditioning regimen for bone marrow transplantation (BMT). Cytotoxicity limits the use of this life-saving therapy, but the underlying mechanisms remain poorly defined. Here, we use the syngeneic mouse BMT model to test the hypothesis that lethal radiation damages ti...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446913/ https://www.ncbi.nlm.nih.gov/pubmed/32760056 http://dx.doi.org/10.1371/journal.pbio.3000807 |