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Evaluating modified diets and dietary supplement therapies for reducing muscle lipid accumulation and improving muscle function in neurofibromatosis type 1 (NF1)

Neurofibromatosis type 1 (NF1) is a genetic disorder that affects a range of tissue systems, however the associated muscle weakness and fatigability can have a profound impact on quality of life. Prior studies using the limb-specific Nf1 knockout mouse (Nf1(Prx1)(-/-)) revealed an accumulation of in...

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Detalles Bibliográficos
Autores principales: Vasiljevski, Emily R., Houweling, Peter J., Rupasinghe, Thusitha, Kaur, Tarneet, Summers, Matthew A., Roessner, Ute, Little, David G., Schindeler, Aaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446925/
https://www.ncbi.nlm.nih.gov/pubmed/32810864
http://dx.doi.org/10.1371/journal.pone.0237097