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Impaired therapeutic efficacy of bone marrow cells from post-myocardial infarction patients in the TIME and LateTIME clinical trials

Implantation of bone marrow-derived cells (BMCs) into mouse hearts post-myocardial infarction (MI) limits cardiac functional decline. However, clinical trials of post-MI BMC therapy have yielded conflicting results. While most laboratory experiments use healthy BMC donor mice, clinical trials use po...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoyin, Chacon, Lourdes I., Derakhshandeh, Ronak, Rodriguez, Hilda J., Han, Daniel D., Kostyushev, Dmitry S., Henry, Timothy D., Traverse, Jay H., Moyé, Lem, Simari, Robert D., Taylor, Doris A., Springer, Matthew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446972/
https://www.ncbi.nlm.nih.gov/pubmed/32841277
http://dx.doi.org/10.1371/journal.pone.0237401