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Leptospiral LPS escapes mouse TLR4 internalization and TRIF‑associated antimicrobial responses through O antigen and associated lipoproteins

Leptospirosis is a worldwide re-emerging zoonosis caused by pathogenic Leptospira spp. All vertebrate species can be infected; humans are sensitive hosts whereas other species, such as rodents, may become long-term renal carrier reservoirs. Upon infection, innate immune responses are initiated by re...

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Detalles Bibliográficos
Autores principales: Bonhomme, Delphine, Santecchia, Ignacio, Vernel-Pauillac, Frédérique, Caroff, Martine, Germon, Pierre, Murray, Gerald, Adler, Ben, Boneca, Ivo G., Werts, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447051/
https://www.ncbi.nlm.nih.gov/pubmed/32790743
http://dx.doi.org/10.1371/journal.ppat.1008639