Dissecting maternal and fetal genetic effects underlying the associations between maternal phenotypes, birth outcomes, and adult phenotypes: A mendelian-randomization and haplotype-based genetic score analysis in 10,734 mother–infant pairs

BACKGROUND: Many maternal traits are associated with a neonate’s gestational duration, birth weight, and birth length. These birth outcomes are subsequently associated with late-onset health conditions. The causal mechanisms and the relative contributions of maternal and fetal genetic effects behind...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Jing, Bacelis, Jonas, Sole-Navais, Pol, Srivastava, Amit, Juodakis, Julius, Rouse, Amy, Hallman, Mikko, Teramo, Kari, Melbye, Mads, Feenstra, Bjarke, Freathy, Rachel M., Smith, George Davey, Lawlor, Deborah A., Murray, Jeffrey C., Williams, Scott M., Jacobsson, Bo, Muglia, Louis J., Zhang, Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447062/
https://www.ncbi.nlm.nih.gov/pubmed/32841251
http://dx.doi.org/10.1371/journal.pmed.1003305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447062/
https://www.ncbi.nlm.nih.gov/pubmed/32841251
http://dx.doi.org/10.1371/journal.pmed.1003305

Ejemplares similares