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miR-135b-5p enhances the sensitivity of HER-2 positive breast cancer to trastuzumab via binding to cyclin D2

Trastuzumab has led to a marked improvement in the outcomes of patients with human epidermal growth factor receptor 2 (HER-2)-positive breast cancer. However, the effects of trastuzumab on HER-2-positive breast cancer are limited by the emergence of its cardiotoxicside effects. MicroRNA (miR)-135b-5...

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Detalles Bibliográficos
Autores principales: Li, Zhilan, Qin, Yiyu, Chen, Peihong, Luo, Qiong, Shi, Haiyan, Jiang, Xiudi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447305/
https://www.ncbi.nlm.nih.gov/pubmed/32700749
http://dx.doi.org/10.3892/ijmm.2020.4681