Cargando…
miR-135b-5p enhances the sensitivity of HER-2 positive breast cancer to trastuzumab via binding to cyclin D2
Trastuzumab has led to a marked improvement in the outcomes of patients with human epidermal growth factor receptor 2 (HER-2)-positive breast cancer. However, the effects of trastuzumab on HER-2-positive breast cancer are limited by the emergence of its cardiotoxicside effects. MicroRNA (miR)-135b-5...
Autores principales: | Li, Zhilan, Qin, Yiyu, Chen, Peihong, Luo, Qiong, Shi, Haiyan, Jiang, Xiudi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447305/ https://www.ncbi.nlm.nih.gov/pubmed/32700749 http://dx.doi.org/10.3892/ijmm.2020.4681 |
Ejemplares similares
-
miR‐200c suppresses stemness and increases cellular sensitivity to trastuzumab in HER2+ breast cancer
por: Tang, Hailin, et al.
Publicado: (2019) -
miR-125a Induces HER2 Expression and Sensitivity to Trastuzumab in Triple-Negative Breast Cancer Lines
por: Ninio-Many, Lihi, et al.
Publicado: (2020) -
MiR-221 promotes trastuzumab-resistance and metastasis in HER2-positive breast cancers by targeting PTEN
por: Ye, Xingming, et al.
Publicado: (2014) -
Involvement of miR-770-5p in trastuzumab response in HER2 positive breast cancer cells
por: Noyan, Senem, et al.
Publicado: (2019) -
Upregulation of miR-125b is associated with poor prognosis and trastuzumab resistance in HER2-positive gastric cancer
por: Sui, Minghua, et al.
Publicado: (2017)