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A comprehensive analysis of RHOA mutation positive and negative angioimmunoblastic T-cell lymphomas by targeted deep sequencing, expression profiling and single cell digital image analysis

Angioimmunoblastic T-cell lymphoma (AITL) is a uniquely aggressive mature T-cell neoplasm. In recent years, recurrent genetic mutations in ras homolog family member A (RHOA), tet methylcytosine dioxygenase 2 (TET2), DNA methyltransferase 3 alpha (DNMT3A) and isocitrate dehydrogenase [NADP(+)] 2 (IDH...

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Detalles Bibliográficos
Autores principales: Butzmann, Alexandra, Sridhar, Kaushik, Jangam, Diwash, Kumar, Jyoti, Sahoo, Malaya Kumar, Shahmarvand, Nahid, Warnke, Roger, Rangasamy, Elumalai, Pinsky, Benjamin Alan, Ohgami, Robert Shigeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447311/
https://www.ncbi.nlm.nih.gov/pubmed/32945366
http://dx.doi.org/10.3892/ijmm.2020.4686