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Activation-induced cytidine deaminase overexpression in double-hit lymphoma: potential target for novel anticancer therapy

Activation-induced cytidine deaminase (AID) is one kind of the mutant enzymes, which target regulating the immunoglobulin (Ig) gene in Burkitt’s lymphoma to initiate class switch recombination (CSR), resulting in c-Myc chromosomal translocation. However, it is not clear that whether AID induces c-My...

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Detalles Bibliográficos
Autores principales: Zhang, Jingcheng, Shi, Yifen, Zhao, Mingzhe, Hu, Huixian, Huang, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447639/
https://www.ncbi.nlm.nih.gov/pubmed/32843697
http://dx.doi.org/10.1038/s41598-020-71058-y