Characterization of FLT3-ITD(mut) acute myeloid leukemia: molecular profiling of leukemic precursor cells

Acute myeloid leukemia (AML) with FLT3-ITD mutations (FLT3-ITD(mut)) remains a therapeutic challenge, with a still high relapse rate, despite targeted treatment with tyrosine kinase inhibitors. In this disease, the CD34/CD123/CD25/CD99+ leukemic precursor cells (LPCs) phenotype predicts for FLT3-ITD...

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Detalles Bibliográficos
Autores principales: Travaglini, Serena, Angelini, Daniela Francesca, Alfonso, Valentina, Guerrera, Gisella, Lavorgna, Serena, Divona, Mariadomenica, Nardozza, Anna Maria, Consalvo, Maria Irno, Fabiani, Emiliano, De Bardi, Marco, Neri, Benedetta, Forghieri, Fabio, Marchesi, Francesco, Paterno, Giovangiacinto, Cerretti, Raffaella, Barragan, Eva, Fiori, Valentina, Dominici, Sabrina, Del Principe, Maria Ilaria, Venditti, Adriano, Battistini, Luca, Arcese, William, Lo-Coco, Francesco, Voso, Maria Teresa, Ottone, Tiziana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447750/
https://www.ncbi.nlm.nih.gov/pubmed/32843624
http://dx.doi.org/10.1038/s41408-020-00352-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447750/
https://www.ncbi.nlm.nih.gov/pubmed/32843624
http://dx.doi.org/10.1038/s41408-020-00352-9

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