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Molecular mechanism of mitochondrial phosphatidate transfer by Ups1

Cardiolipin, an essential mitochondrial physiological regulator, is synthesized from phosphatidic acid (PA) in the inner mitochondrial membrane (IMM). PA is synthesized in the endoplasmic reticulum and transferred to the IMM via the outer mitochondrial membrane (OMM) under mediation by the Ups1/Mdm3...

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Detalles Bibliográficos
Autores principales: Lu, Jiuwei, Chan, Chun, Yu, Leiye, Fan, Jun, Sun, Fei, Zhai, Yujia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447767/
https://www.ncbi.nlm.nih.gov/pubmed/32843686
http://dx.doi.org/10.1038/s42003-020-01121-x