Regulation of epithelial-mesenchymal transition and organoid morphogenesis by a novel TGFβ-TCF7L2 isoform-specific signaling pathway

Alternative splicing contributes to diversification of gene function, yet consequences of splicing on functions of specific gene products is poorly understood. The major transcription factor TCF7L2 undergoes alternative splicing but the biological significance of TCF7L2 isoforms has remained largely...

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Detalles Bibliográficos
Autores principales: Karve, Kunal, Netherton, Stuart, Deng, Lili, Bonni, Azad, Bonni, Shirin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447769/
https://www.ncbi.nlm.nih.gov/pubmed/32843642
http://dx.doi.org/10.1038/s41419-020-02905-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447769/
https://www.ncbi.nlm.nih.gov/pubmed/32843642
http://dx.doi.org/10.1038/s41419-020-02905-z

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