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Breast cancer gene expression datasets do not reflect the disease at the population level

Publicly available tumor gene expression datasets are widely reanalyzed, but it is unclear how representative they are of clinical populations. Estimations of molecular subtype classification and prognostic gene signatures were calculated for 16,130 patients from 70 breast cancer datasets. Collated...

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Detalles Bibliográficos
Autores principales: Xie, Yanping, Davis Lynn, Brittny C., Moir, Nicholas, Cameron, David A., Figueroa, Jonine D., Sims, Andrew H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447772/
https://www.ncbi.nlm.nih.gov/pubmed/32885043
http://dx.doi.org/10.1038/s41523-020-00180-x