Atrogin1-induced loss of aquaporin 4 in myocytes leads to skeletal muscle atrophy

The water channel aquaporin 4 (AQP4) regulates the flux of water across the cell membrane, maintaining cellular homeostasis. Since AQP4 is enriched in the sarcolemma of skeletal muscle, a functional defect in AQP4 may cause skeletal muscle dysfunction. To investigate a novel mechanism underlying ske...

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Detalles Bibliográficos
Autores principales: Chung, Seok Won, Kim, Ja-Yeon, Yoon, Jong Pil, Suh, Dong Won, Yeo, Woo Jin, Lee, Yong-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447774/
https://www.ncbi.nlm.nih.gov/pubmed/32843684
http://dx.doi.org/10.1038/s41598-020-71167-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447774/
https://www.ncbi.nlm.nih.gov/pubmed/32843684
http://dx.doi.org/10.1038/s41598-020-71167-8

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