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Atrogin1-induced loss of aquaporin 4 in myocytes leads to skeletal muscle atrophy
The water channel aquaporin 4 (AQP4) regulates the flux of water across the cell membrane, maintaining cellular homeostasis. Since AQP4 is enriched in the sarcolemma of skeletal muscle, a functional defect in AQP4 may cause skeletal muscle dysfunction. To investigate a novel mechanism underlying ske...
Autores principales: | Chung, Seok Won, Kim, Ja-Yeon, Yoon, Jong Pil, Suh, Dong Won, Yeo, Woo Jin, Lee, Yong-Soo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447774/ https://www.ncbi.nlm.nih.gov/pubmed/32843684 http://dx.doi.org/10.1038/s41598-020-71167-8 |
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