Heterologous expression of high-activity cytochrome P450 in mammalian cells

The evaluation of Cytochrome P450 (CYP) enzymatic activity is essential to estimate drug pharmacokinetics. Numerous CYP allelic variants have been identified; the functional characterisation of these variants is required for their application in precision medicine. Results from heterologous expressi...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumondai, Masaki, Hishinuma, Eiji, Gutiérrez Rico, Evelyn Marie, Ito, Akio, Nakanishi, Yuya, Saigusa, Daisuke, Hirasawa, Noriyasu, Hiratsuka, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447777/
https://www.ncbi.nlm.nih.gov/pubmed/32843676
http://dx.doi.org/10.1038/s41598-020-71035-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447777/
https://www.ncbi.nlm.nih.gov/pubmed/32843676
http://dx.doi.org/10.1038/s41598-020-71035-5

Ejemplares similares