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Depletion of senescent-like neuronal cells alleviates cisplatin-induced peripheral neuropathy in mice

Chemotherapy-induced peripheral neuropathy is among the most common dose-limiting adverse effects of cancer treatment, leading to dose reduction and discontinuation of life-saving chemotherapy and a permanently impaired quality of life for patients. Currently, no effective treatment or prevention is...

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Detalles Bibliográficos
Autores principales: Acklin, Scarlett, Zhang, Manchao, Du, Wuying, Zhao, Xin, Plotkin, Matthew, Chang, Jianhui, Campisi, Judith, Zhou, Daohong, Xia, Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447787/
https://www.ncbi.nlm.nih.gov/pubmed/32843706
http://dx.doi.org/10.1038/s41598-020-71042-6