Genomic profiling of the transcription factor Zfp148 and its impact on the p53 pathway

Recent data suggest that the transcription factor Zfp148 represses activation of the tumor suppressor p53 in mice and that therapeutic targeting of the human orthologue ZNF148 could activate the p53 pathway without causing detrimental side effects. We have previously shown that Zfp148 deficiency pro...

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Detalles Bibliográficos
Autores principales: Zou, Zhiyuan V., Gul, Nadia, Lindberg, Markus, Bokhari, Abdulmalik A., Eklund, Ella M., Garellick, Viktor, Patel, Angana A. H., Dzanan, Jozefina J., Titmuss, Ben O., Le Gal, Kristell, Johansson, Inger, Tivesten, Åsa, Forssell-Aronsson, Eva, Bergö, Martin O., Staffas, Anna, Larsson, Erik, Sayin, Volkan I., Lindahl, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447789/
https://www.ncbi.nlm.nih.gov/pubmed/32843651
http://dx.doi.org/10.1038/s41598-020-70824-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447789/
https://www.ncbi.nlm.nih.gov/pubmed/32843651
http://dx.doi.org/10.1038/s41598-020-70824-2

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