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Genomic profiling of the transcription factor Zfp148 and its impact on the p53 pathway
Recent data suggest that the transcription factor Zfp148 represses activation of the tumor suppressor p53 in mice and that therapeutic targeting of the human orthologue ZNF148 could activate the p53 pathway without causing detrimental side effects. We have previously shown that Zfp148 deficiency pro...
Autores principales: | Zou, Zhiyuan V., Gul, Nadia, Lindberg, Markus, Bokhari, Abdulmalik A., Eklund, Ella M., Garellick, Viktor, Patel, Angana A. H., Dzanan, Jozefina J., Titmuss, Ben O., Le Gal, Kristell, Johansson, Inger, Tivesten, Åsa, Forssell-Aronsson, Eva, Bergö, Martin O., Staffas, Anna, Larsson, Erik, Sayin, Volkan I., Lindahl, Per |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447789/ https://www.ncbi.nlm.nih.gov/pubmed/32843651 http://dx.doi.org/10.1038/s41598-020-70824-2 |
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