TRPV4 activates the Cdc42/N-wasp pathway to promote glioblastoma invasion by altering cellular protrusions

The invasion ability of glioblastoma (GBM) causes tumor cells to infiltrate the surrounding brain parenchyma and leads to poor outcomes. Transient receptor potential vanilloid 4 (TRPV4) exhibits a remarkable role in cancer cell motility, but the contribution of TRPV4 to glioblastoma metastasis is no...

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Detalles Bibliográficos
Autores principales: Yang, Wei, Wu, Peng-fei, Ma, Jian-xing, Liao, Mao-jun, Xu, Lun-shan, Yi, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447819/
https://www.ncbi.nlm.nih.gov/pubmed/32843668
http://dx.doi.org/10.1038/s41598-020-70822-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447819/
https://www.ncbi.nlm.nih.gov/pubmed/32843668
http://dx.doi.org/10.1038/s41598-020-70822-4

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