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Direct Readout of Neural Stem Cell Transgenesis with an Integration-Coupled Gene Expression Switch
Stable genomic integration of exogenous transgenes is essential in neurodevelopmental and stem cell studies. Despite tools driving increasingly efficient genomic insertion with DNA vectors, transgenesis remains fundamentally hindered by the impossibility of distinguishing integrated from episomal tr...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447981/ https://www.ncbi.nlm.nih.gov/pubmed/32559415 http://dx.doi.org/10.1016/j.neuron.2020.05.038 |