Direct Readout of Neural Stem Cell Transgenesis with an Integration-Coupled Gene Expression Switch

Stable genomic integration of exogenous transgenes is essential in neurodevelopmental and stem cell studies. Despite tools driving increasingly efficient genomic insertion with DNA vectors, transgenesis remains fundamentally hindered by the impossibility of distinguishing integrated from episomal tr...

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Detalles Bibliográficos
Autores principales: Kumamoto, Takuma, Maurinot, Franck, Barry-Martinet, Raphaëlle, Vaslin, Célia, Vandormael-Pournin, Sandrine, Le, Mickaël, Lerat, Marion, Niculescu, Dragos, Cohen-Tannoudji, Michel, Rebsam, Alexandra, Loulier, Karine, Nedelec, Stéphane, Tozer, Samuel, Livet, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447981/
https://www.ncbi.nlm.nih.gov/pubmed/32559415
http://dx.doi.org/10.1016/j.neuron.2020.05.038

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