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Ru(II) Complexes Bearing O, O-Chelated Ligands Induced Apoptosis in A549 Cells through the Mitochondrial Apoptotic Pathway

Two new Ru(II) complexes containing O, O-chelated ligands, Ru(dip)(2)(SA) (Ru-1) and Ru(dmp)(2)(SA) (Ru-2) (dip = 4,7-diphenyl-1,10-phenanthroline; dmp = 2,9-dimethyl-1,10-phenanthroline; SA = salicylate) were synthesized to evaluate their cytotoxicity in vitro. These complexes were found to exhibit...

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Detalles Bibliográficos
Autores principales: Chen, Jincan, Wang, Jie, Deng, Yuanyuan, Wang, Tao, Miao, Tifang, Li, Chengpeng, Cai, Xianhong, Liu, Ying, Henri, Justin, Chen, Lanmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448123/
https://www.ncbi.nlm.nih.gov/pubmed/32879623
http://dx.doi.org/10.1155/2020/8890950