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Acetylation of Surface Carbohydrates in Bacterial Pathogens Requires Coordinated Action of a Two-Domain Membrane-Bound Acyltransferase

Membrane bound acyltransferase-3 (AT3) domain-containing proteins are implicated in a wide range of carbohydrate O-acyl modifications, but their mechanism of action is largely unknown. O-antigen acetylation by AT3 domain-containing acetyltransferases of Salmonella spp. can generate a specific immune...

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Detalles Bibliográficos
Autores principales: Pearson, Caroline R., Tindall, Sarah N., Herman, Reyme, Jenkins, Huw T., Bateman, Alex, Thomas, Gavin H., Potts, Jennifer R., Van der Woude, Marjan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448272/
https://www.ncbi.nlm.nih.gov/pubmed/32843546
http://dx.doi.org/10.1128/mBio.01364-20