Heterologous Expression of the Unusual Terreazepine Biosynthetic Gene Cluster Reveals a Promising Approach for Identifying New Chemical Scaffolds

Advances in genome sequencing have revitalized natural product discovery efforts, revealing the untapped biosynthetic potential of fungi. While the volume of genomic data continues to expand, discovery efforts are slowed due to the time-consuming nature of experiments required to characterize new mo...

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Detalles Bibliográficos
Autores principales: Caesar, Lindsay K., Robey, Matthew T., Swyers, Michael, Islam, Md N., Ye, Rosa, Vagadia, Purav P., Schiltz, Gary E., Thomas, Paul M., Wu, Chengcang C., Kelleher, Neil L., Keller, Nancy P., Bok, Jin Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448278/
https://www.ncbi.nlm.nih.gov/pubmed/32843555
http://dx.doi.org/10.1128/mBio.01691-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448278/
https://www.ncbi.nlm.nih.gov/pubmed/32843555
http://dx.doi.org/10.1128/mBio.01691-20

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