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Heterologous Expression of the Unusual Terreazepine Biosynthetic Gene Cluster Reveals a Promising Approach for Identifying New Chemical Scaffolds
Advances in genome sequencing have revitalized natural product discovery efforts, revealing the untapped biosynthetic potential of fungi. While the volume of genomic data continues to expand, discovery efforts are slowed due to the time-consuming nature of experiments required to characterize new mo...
Autores principales: | Caesar, Lindsay K., Robey, Matthew T., Swyers, Michael, Islam, Md N., Ye, Rosa, Vagadia, Purav P., Schiltz, Gary E., Thomas, Paul M., Wu, Chengcang C., Kelleher, Neil L., Keller, Nancy P., Bok, Jin Woo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448278/ https://www.ncbi.nlm.nih.gov/pubmed/32843555 http://dx.doi.org/10.1128/mBio.01691-20 |
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