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Intraspecies Signaling between Common Variants of Pseudomonas aeruginosa Increases Production of Quorum-Sensing-Controlled Virulence Factors

The opportunistic pathogen Pseudomonas aeruginosa damages hosts through the production of diverse secreted products, many of which are regulated by quorum sensing (QS). The lasR gene, which encodes a central QS regulator, is frequently mutated in clinical isolates from chronic infections, and loss o...

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Detalles Bibliográficos
Autores principales: Mould, Dallas L., Botelho, Nico J., Hogan, Deborah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448281/
https://www.ncbi.nlm.nih.gov/pubmed/32843558
http://dx.doi.org/10.1128/mBio.01865-20