IL-22 hinders antiviral T cell responses and exacerbates ZIKV encephalitis in immunocompetent neonatal mice

BACKGROUND: The Zika virus (ZIKV) outbreak that occurred in multiple countries was linked to increased risk of nervous system injuries and congenital defects. However, host immunity- and immune-mediated pathogenesis in ZIKV infection are not well understood. Interleukin-22 (IL-22) is a crucial cytok...

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Detalles Bibliográficos
Autores principales: Liang, Yuejin, Yi, Panpan, Ru, Wenjuan, Jie, Zuliang, Wang, Hui, Ghanayem, Tamer, Wang, Xiaofang, Alamer, Edrous, Liu, Jinjun, Hu, Haitao, Soong, Lynn, Cai, Jiyang, Sun, Jiaren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448338/
https://www.ncbi.nlm.nih.gov/pubmed/32843067
http://dx.doi.org/10.1186/s12974-020-01928-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448338/
https://www.ncbi.nlm.nih.gov/pubmed/32843067
http://dx.doi.org/10.1186/s12974-020-01928-9

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