Xanthohumol targets the ERK1/2-Fra1 signaling axis to reduce cyclin D1 expression and inhibit non-small cell lung cancer

High expression of cyclin D1 has a crucial role in the maintenance of unlimited cell growth in human cancer cells. The present study indicated that cyclin D1 was overexpressed in human non-small cell lung cancer (NSCLC) tumor tissues and cell lines. Knockout of cyclin D1 suppressed NSCLC cell growth...

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Detalles Bibliográficos
Autores principales: Gao, Feng, Li, Ming, Zhou, Li, Liu, Wenbin, Zuo, Huilan, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448415/
https://www.ncbi.nlm.nih.gov/pubmed/32945473
http://dx.doi.org/10.3892/or.2020.7697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448415/
https://www.ncbi.nlm.nih.gov/pubmed/32945473
http://dx.doi.org/10.3892/or.2020.7697

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