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RAD52 aptamer regulates DNA damage repair and STAT3 in BRCA1/BRCA2-deficient human acute myeloid leukemia

RAD52 (Radiation sensitive 52) is a key factor in DNA damage repair (DDR) bypass, which participates in single-strand annealing (SSA) after DNA damage end excision, while breast cancer type 1 susceptibility protein (BRCA1)/breast cancer type 2 susceptibility protein (BRCA2) play critical roles in ho...

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Detalles Bibliográficos
Autores principales: Xu, Yichuan, Lin, Yansi, Luo, Yuxuan, Yang, Yanling, Long, Bing, Fang, Zhigang, Liu, Lingling, Zhang, Jingwen, Zhang, Xiangzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448423/
https://www.ncbi.nlm.nih.gov/pubmed/32945515
http://dx.doi.org/10.3892/or.2020.7723