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Inactivation of AKT/NF-κB signaling by eurycomalactone decreases human NSCLC cell viability and improves the chemosensitivity to cisplatin

The high activation of protein kinase B (AKT)/nuclear factor-κB (NF-κB) signaling has often been associated with the induction of non-small cell lung cancer (NSCLC) cell survival and resistance to cisplatin, which is one of the most widely used chemotherapeutic drugs in the treatment of NSCLC. The i...

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Detalles Bibliográficos
Autores principales: Dukaew, Nahathai, Chairatvit, Kongthawat, Pitchakarn, Pornsiri, Imsumran, Arisa, Karinchai, Jirarat, Tuntiwechapikul, Wirote, Wongnoppavich, Ariyaphong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448543/
https://www.ncbi.nlm.nih.gov/pubmed/32945500
http://dx.doi.org/10.3892/or.2020.7710