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Overexpression of close homolog of L1 enhances the chemosensitivity of lung cancer cells via inhibition of the Akt pathway

Drug resistance leads to tumor relapse and further progression during chemotherapy in lung cancer. Close homolog of L1 (CHL1) has been identified as a tumor suppressor in most malignancies. However, to the best of our knowledge, whether CHL1 mediates chemoresistance remains unknown. The present stud...

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Detalles Bibliográficos
Autores principales: Cai, Xiangdao, Hu, Bang, Liu, Sheng, Liu, Maolin, Huang, Yunhe, Lei, Peng, Zhang, Zhi, He, Zhiwei, Zhang, Linquan, Huang, Rimao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448558/
https://www.ncbi.nlm.nih.gov/pubmed/32863924
http://dx.doi.org/10.3892/ol.2020.11972