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Cointegration as a mechanism for the evolution of a KPC-producing multidrug resistance plasmid in Proteus mirabilis

The incidence and transmission of Klebsiella pneumoniae carbapenemase (KPC) producing plasmids have been well documented. However, the evolutionary dynamics of KPC plasmids and their fitness costs are not well characterized. Here, two carbapenemase-producing plasmids from Proteus mirabilis, pT18 and...

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Detalles Bibliográficos
Autores principales: Hua, Xiaoting, Zhang, Linyue, Moran, Robert A., Xu, Qingye, Sun, Long, van Schaik, Willem, Yu, Yunsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448864/
https://www.ncbi.nlm.nih.gov/pubmed/32438864
http://dx.doi.org/10.1080/22221751.2020.1773322