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Molecular surveillance reveals the presence of pfhrp2 and pfhrp3 gene deletions in Plasmodium falciparum parasite populations in Uganda, 2017–2019

BACKGROUND: Histidine-rich protein-2 (HRP2)-based rapid diagnostic tests (RDTs) are the only RDTs recommended for malaria diagnosis in Uganda. However, the emergence of Plasmodium falciparum histidine rich protein 2 and 3 (pfhrp2 and pfhrp3) gene deletions threatens their usefulness as malaria diagn...

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Detalles Bibliográficos
Autores principales: Bosco, Agaba B., Anderson, Karen, Gresty, Karryn, Prosser, Christiane, Smith, David, Nankabirwa, Joaniter I., Nsobya, Sam, Yeka, Adoke, Opigo, Jimmy, Gonahasa, Samuel, Namubiru, Rhoda, Arinaitwe, Emmanuel, Mbaka, Paul, Kissa, John, Won, Sungho, Lee, Bora, Lim, Chae Seung, Karamagi, Charles, Cunningham, Jane, Nakayaga, Joan K., Kamya, Moses R., Cheng, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449024/
https://www.ncbi.nlm.nih.gov/pubmed/32843041
http://dx.doi.org/10.1186/s12936-020-03362-x