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CXCR4(+) cells are increased in lung tissue of patients with idiopathic pulmonary fibrosis

BACKGROUND: CXCR4, a transmembrane-receptor located on epithelial cells that is activated by CXCL12, may have a role in IPF via migration of CXCR4(+) fibrocytes to the lung. However, its expression has not been fully characterised in idiopathic pulmonary fibrosis (IPF) or other fibrotic interstitial...

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Detalles Bibliográficos
Autores principales: Jaffar, Jade, Griffiths, Kate, Oveissi, Sara, Duan, Mubing, Foley, Michael, Glaspole, Ian, Symons, Karen, Organ, Louise, Westall, Glen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449054/
https://www.ncbi.nlm.nih.gov/pubmed/32843095
http://dx.doi.org/10.1186/s12931-020-01467-0