A new mechanism for a familiar mutation – bovine DGAT1 K232A modulates gene expression through multi-junction exon splice enhancement

BACKGROUND: The DGAT1 gene encodes an enzyme responsible for catalysing the terminal reaction in mammary triglyceride synthesis, and underpins a well-known pleiotropic quantitative trait locus (QTL) with a large influence on milk composition phenotypes. Since first described over 15 years ago, a pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Fink, Tania, Lopdell, Thomas J., Tiplady, Kathryn, Handley, Renee, Johnson, Thomas J. J., Spelman, Richard J., Davis, Stephen R., Snell, Russell G., Littlejohn, Mathew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449055/
https://www.ncbi.nlm.nih.gov/pubmed/32847516
http://dx.doi.org/10.1186/s12864-020-07004-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449055/
https://www.ncbi.nlm.nih.gov/pubmed/32847516
http://dx.doi.org/10.1186/s12864-020-07004-z

Ejemplares similares