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Nonstationary Pharmacokinetics of Caspofungin in ICU Patients
Standard dosing of caspofungin in critically ill patients has been reported to result in lower drug exposure, which can lead to subtherapeutic 24-h area under the curve to MIC (AUC(0–24)/MIC) ratios. The aim of the study was to investigate the population pharmacokinetics of caspofungin in a cohort o...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449161/ https://www.ncbi.nlm.nih.gov/pubmed/32601169 http://dx.doi.org/10.1128/AAC.00345-20 |