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Nonstationary Pharmacokinetics of Caspofungin in ICU Patients

Standard dosing of caspofungin in critically ill patients has been reported to result in lower drug exposure, which can lead to subtherapeutic 24-h area under the curve to MIC (AUC(0–24)/MIC) ratios. The aim of the study was to investigate the population pharmacokinetics of caspofungin in a cohort o...

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Detalles Bibliográficos
Autores principales: Borsuk-De Moor, Agnieszka, Sysiak-Sławecka, Justyna, Rypulak, Elżbieta, Borys, Michał, Piwowarczyk, Paweł, Raszewski, Grzegorz, Onichimowski, Dariusz, Czuczwar, Mirosław, Wiczling, Paweł
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449161/
https://www.ncbi.nlm.nih.gov/pubmed/32601169
http://dx.doi.org/10.1128/AAC.00345-20