Candida glabrata Transcription Factor Rpn4 Mediates Fluconazole Resistance through Regulation of Ergosterol Biosynthesis and Plasma Membrane Permeability

The ability to acquire azole resistance is an emblematic trait of the fungal pathogen Candida glabrata. Understanding the molecular basis of azole resistance in this pathogen is crucial for designing more suitable therapeutic strategies. This study shows that the C. glabrata transcription factor (TF...

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Detalles Bibliográficos
Autores principales: Pais, Pedro, Califórnia, Raquel, Galocha, Mónica, Viana, Romeu, Ola, Mihaela, Cavalheiro, Mafalda, Takahashi-Nakaguchi, Azusa, Chibana, Hiroji, Butler, Geraldine, Teixeira, Miguel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Mechanisms of Resistance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449212/
https://www.ncbi.nlm.nih.gov/pubmed/32571817
http://dx.doi.org/10.1128/AAC.00554-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449212/
https://www.ncbi.nlm.nih.gov/pubmed/32571817
http://dx.doi.org/10.1128/AAC.00554-20

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