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Bcl-6 is the nexus transcription factor of T follicular helper cells (T(FH)) via repressor-of-repressor circuits
T follicular helper (T(FH)) cells are a distinct type of CD4(+) T cells that are essential for most antibody and B lymphocyte responses. T(FH) cell regulation and dysregulation is involved in a range of diseases. Bcl-6 is the lineage defining transcription factor of T(FH) cells and its activity is e...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449381/ https://www.ncbi.nlm.nih.gov/pubmed/32572238 http://dx.doi.org/10.1038/s41590-020-0706-5 |