Cryptic genetic variation enhances primate L1 retrotransposon survival by enlarging the functional coiled coil sequence space of ORF1p

Accounting for continual evolution of deleterious L1 retrotransposon families, which can contain hundreds to thousands of members remains a major issue in mammalian biology. L1 activity generated upwards of 40% of some mammalian genomes, including humans where they remain active, causing genetic def...

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Detalles Bibliográficos
Autores principales: Furano, Anthony V., Jones, Charlie E., Periwal, Vipul, Callahan, Kathryn E., Walser, Jean-Claude, Cook, Pamela R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449397/
https://www.ncbi.nlm.nih.gov/pubmed/32797042
http://dx.doi.org/10.1371/journal.pgen.1008991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449397/
https://www.ncbi.nlm.nih.gov/pubmed/32797042
http://dx.doi.org/10.1371/journal.pgen.1008991

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