Machine Learning based histology phenotyping to investigate the epidemiologic and genetic basis of adipocyte morphology and cardiometabolic traits

Genetic studies have recently highlighted the importance of fat distribution, as well as overall adiposity, in the pathogenesis of obesity-associated diseases. Using a large study (n = 1,288) from 4 independent cohorts, we aimed to investigate the relationship between mean adipocyte area and obesity...

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Detalles Bibliográficos
Autores principales: Glastonbury, Craig A., Pulit, Sara L., Honecker, Julius, Censin, Jenny C., Laber, Samantha, Yaghootkar, Hanieh, Rahmioglu, Nilufer, Pastel, Emilie, Kos, Katerina, Pitt, Andrew, Hudson, Michelle, Nellåker, Christoffer, Beer, Nicola L., Hauner, Hans, Becker, Christian M., Zondervan, Krina T., Frayling, Timothy M., Claussnitzer, Melina, Lindgren, Cecilia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449405/
https://www.ncbi.nlm.nih.gov/pubmed/32797044
http://dx.doi.org/10.1371/journal.pcbi.1008044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449405/
https://www.ncbi.nlm.nih.gov/pubmed/32797044
http://dx.doi.org/10.1371/journal.pcbi.1008044

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