Footprint of the host restriction factors APOBEC3 on the genome of human viruses

APOBEC3 enzymes are innate immune effectors that introduce mutations into viral genomes. These enzymes are cytidine deaminases which transform cytosine into uracil. They preferentially mutate cytidine preceded by thymidine making the 5’TC motif their favored target. Viruses have evolved different st...

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Detalles Bibliográficos
Autores principales: Poulain, Florian, Lejeune, Noémie, Willemart, Kévin, Gillet, Nicolas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449416/
https://www.ncbi.nlm.nih.gov/pubmed/32797103
http://dx.doi.org/10.1371/journal.ppat.1008718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449416/
https://www.ncbi.nlm.nih.gov/pubmed/32797103
http://dx.doi.org/10.1371/journal.ppat.1008718

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