Cargando…
Tumor-infiltrating CD62L(+)PD-1(-)CD8 T cells retain proliferative potential via Bcl6 expression and replenish effector T cells within the tumor
Tumor antigen–primed CD8 T cells differentiate into effector T cells that kill tumor cells rapidly, whereas durable responses of CD8 T cells are required to cope with long-lasting tumor growth. However, it is not well known how persisting CD8 T cells are generated. In this study, we analyzed CD8 T c...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449457/ https://www.ncbi.nlm.nih.gov/pubmed/32845913 http://dx.doi.org/10.1371/journal.pone.0237646 |