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Tumor-infiltrating CD62L(+)PD-1(-)CD8 T cells retain proliferative potential via Bcl6 expression and replenish effector T cells within the tumor

Tumor antigen–primed CD8 T cells differentiate into effector T cells that kill tumor cells rapidly, whereas durable responses of CD8 T cells are required to cope with long-lasting tumor growth. However, it is not well known how persisting CD8 T cells are generated. In this study, we analyzed CD8 T c...

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Detalles Bibliográficos
Autores principales:	Gong, Yu, Suzuki, Toshihiro, Kozono, Haruo, Kubo, Masato, Nakano, Naoko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449457/ https://www.ncbi.nlm.nih.gov/pubmed/32845913 http://dx.doi.org/10.1371/journal.pone.0237646

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