Sequencing and imputation in GWAS: Cost‐effective strategies to increase power and genomic coverage across diverse populations

A key aim for current genome‐wide association studies (GWAS) is to interrogate the full spectrum of genetic variation underlying human traits, including rare variants, across populations. Deep whole‐genome sequencing is the gold standard to fully capture genetic variation, but remains prohibitively...

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Detalles Bibliográficos
Autores principales: Quick, Corbin, Anugu, Pramod, Musani, Solomon, Weiss, Scott T., Burchard, Esteban G., White, Marquitta J., Keys, Kevin L., Cucca, Francesco, Sidore, Carlo, Boehnke, Michael, Fuchsberger, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449570/
https://www.ncbi.nlm.nih.gov/pubmed/32519380
http://dx.doi.org/10.1002/gepi.22326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449570/
https://www.ncbi.nlm.nih.gov/pubmed/32519380
http://dx.doi.org/10.1002/gepi.22326

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