Cargando…

Application of a Biologically Contained Reporter System To Study Gain-of-Function H5N1 Influenza A Viruses with Pandemic Potential

Natural adaptation of an antigenically novel avian influenza A virus (IAV) to be transmitted efficiently in humans has the potential to trigger a devastating pandemic. Understanding viral genetic determinants underlying adaptation is therefore critical for pandemic preparedness, as the knowledge gai...

Descripción completa

Detalles Bibliográficos
Autores principales: Spieler, Eva E., Moritz, Eva, Stertz, Silke, Hale, Benjamin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449622/
https://www.ncbi.nlm.nih.gov/pubmed/32848003
http://dx.doi.org/10.1128/mSphere.00423-20