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Application of a Biologically Contained Reporter System To Study Gain-of-Function H5N1 Influenza A Viruses with Pandemic Potential
Natural adaptation of an antigenically novel avian influenza A virus (IAV) to be transmitted efficiently in humans has the potential to trigger a devastating pandemic. Understanding viral genetic determinants underlying adaptation is therefore critical for pandemic preparedness, as the knowledge gai...
Autores principales: | Spieler, Eva E., Moritz, Eva, Stertz, Silke, Hale, Benjamin G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449622/ https://www.ncbi.nlm.nih.gov/pubmed/32848003 http://dx.doi.org/10.1128/mSphere.00423-20 |
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