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On the cross-population generalizability of gene expression prediction models

The genetic control of gene expression is a core component of human physiology. For the past several years, transcriptome-wide association studies have leveraged large datasets of linked genotype and RNA sequencing information to create a powerful gene-based test of association that has been used in...

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Detalles Bibliográficos
Autores principales: Keys, Kevin L., Mak, Angel C. Y., White, Marquitta J., Eckalbar, Walter L., Dahl, Andrew W., Mefford, Joel, Mikhaylova, Anna V., Contreras, María G., Elhawary, Jennifer R., Eng, Celeste, Hu, Donglei, Huntsman, Scott, Oh, Sam S., Salazar, Sandra, Lenoir, Michael A., Ye, Jimmie C., Thornton, Timothy A., Zaitlen, Noah, Burchard, Esteban G., Gignoux, Christopher R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449671/
https://www.ncbi.nlm.nih.gov/pubmed/32797036
http://dx.doi.org/10.1371/journal.pgen.1008927