DNA polymerase α interacts with H3-H4 and facilitates the transfer of parental histones to lagging strands

How parental histones, the carriers of epigenetic modifications, are deposited onto replicating DNA remains poorly understood. Here, we describe the eSPAN method (enrichment and sequencing of protein-associated nascent DNA) in mouse embryonic stem (ES) cells and use it to detect histone deposition o...

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Detalles Bibliográficos
Autores principales: Li, Zhiming, Hua, Xu, Serra-Cardona, Albert, Xu, Xiaowei, Gan, Songlin, Zhou, Hui, Yang, Wen-Si, Chen, Chun-long, Xu, Rui-Ming, Zhang, Zhiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449674/
https://www.ncbi.nlm.nih.gov/pubmed/32923642
http://dx.doi.org/10.1126/sciadv.abb5820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449674/
https://www.ncbi.nlm.nih.gov/pubmed/32923642
http://dx.doi.org/10.1126/sciadv.abb5820

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