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Systemic anti-inflammatory therapy aided by double-headed nanoparticles in a canine model of acute intraocular inflammation

Novel approaches circumventing blood-ocular barriers in systemic drug delivery are lacking. We hypothesize receptor-mediated delivery of curcumin (CUR) across intestinal and ocular barriers leads to decreased inflammation in a model of lens-induced uveitis. CUR was encapsulated in double-headed poly...

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Detalles Bibliográficos
Autores principales: Ganugula, R., Arora, M., Lepiz, M. A., Niu, Y., Mallick, B. K., Pflugfelder, S. C., Scott, E. M., Kumar, M. N. V. Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449680/
https://www.ncbi.nlm.nih.gov/pubmed/32923645
http://dx.doi.org/10.1126/sciadv.abb7878